Product Overview

Silica Gel G For Thin Layer Chromatography (CAS No. 112926-00-8) is a polar amorphous silica adsorbent formulated for the preparation of thin-layer chromatographic plates. In conventional TLC nomenclature, the G designation indicates a silica material containing a binder system that assists adhesion of the adsorbent layer to the plate during coating, development and visualisation. Surface silanol groups provide the normal-phase adsorption interactions responsible for separation of compounds according to polarity and functional-group character.

The Thin Layer Chromatography product form is intended for laboratory preparation of adherent silica layers and routine planar chromatographic separations. It supports reaction monitoring, qualitative comparison and preparative method development where manually or laboratory-coated TLC plates are appropriate.

Typical Applications

• Preparation of laboratory-coated TLC plates.
• Qualitative separation and identification of organic compounds.
• Monitoring progress of synthetic reactions.
• Comparison of sample and reference migration behaviour.
• Selection of solvent systems before column chromatography.
• Purity screening and fraction monitoring during preparative work.

Common Synonyms

• TLC silica gel G
• Silica gel G
• Binder-containing TLC silica
• Thin-layer chromatography silica gel
• Amorphous silica gel with binder

Storage Conditions

Store tightly closed and dry to minimise moisture uptake that can alter silica activity, coating consistency and chromatographic migration. Protect from organic vapours, dust and chemical contamination that could introduce background spots or occupy active adsorption sites.