Product Overview

Aluminium Oxide Active Neutral For Column Chromatography (CAS No. 1344-28-1) is an activated alumina adsorbent whose surface characteristics are adjusted to a neutral range for chromatographic use. Its porous aluminium oxide structure provides polar adsorption sites that retain mixture components according to their molecular polarity, functional groups, and strength of interaction with the stationary phase. Unlike alumina forms with deliberately acidic or basic surface character, neutral alumina offers a more balanced adsorptive environment for compatible compounds that may require separation without strongly acidic or alkaline conditions.

The active neutral chromatographic form is intended for normal-phase column separation, preparative purification, adsorptive filtration, and sample clean-up. It is particularly useful for separating suitable aldehydes, ketones, quinones, esters, lactones, and glucosides, while also serving as a general alumina stationary phase for reaction-mixture fractionation. Selection of the eluent and loading conditions should reflect the polarity, stability, and retention behaviour of the compounds being processed.

Typical Applications

• Stationary adsorbent for normal-phase column chromatography
• Separation and purification of suitable aldehydes and ketones
• Fractionation of quinones and related oxygen-containing compounds
• Chromatographic separation of compatible esters and lactones
• Isolation and purification of selected glucosides
• Purification of reaction products and synthetic intermediates
• Adsorptive filtration and removal of selected sample impurities
• Sample clean-up before subsequent analytical or characterisation procedures

Neutral activated alumina is documented as a chromatographic adsorbent for aldehydes, ketones, quinones, esters, lactones, and glucosides, while activated aluminium oxides are also used for column chromatography, adsorptive filtration, and solid-phase clean-up.

Common Synonyms

• Aluminium Oxide
• Aluminum Oxide
• Alumina
• Neutral Alumina
• Activated Neutral Alumina
• Active Neutral Aluminium Oxide
• Active Neutral Aluminum Oxide
• Activated Aluminium Oxide, Neutral
• Activated Aluminum Oxide, Neutral
• Neutral Chromatographic Alumina

Storage Conditions

Store in a tightly closed container in a clean, dry location protected from atmospheric moisture, solvent vapours, dust, and other sources of contamination. Activated alumina can adsorb moisture during storage, which may alter its chromatographic activity and retention behaviour. Minimise exposure while dispensing, reseal the container promptly after use, and preserve the material according to any activity or moisture requirements stated in the approved product specification.