Product Overview

Aluminium Oxide Active Acidic For Column Chromatography (CAS No. 1344-28-1) is an activated form of alumina prepared with acidic surface characteristics for use as a polar chromatographic adsorbent. Its porous surface retains mixture components with differing strengths according to their polarity, functional groups, and interaction with the adsorbent, enabling controlled separation as the mobile phase passes through the packed column. The acidic form is technically distinct from neutral and basic alumina and is selected when its particular surface chemistry is appropriate for the compounds being purified.

The active acidic chromatographic form is intended for laboratory-scale column separations, purification of reaction products, and fractionation of complex mixtures. It is particularly associated with the separation of acidic pigments and strongly acidic substances, while its activated adsorptive character supports efficient retention and elution during method development and preparative chromatography. The suitability of the material should be evaluated with consideration of analyte stability, solvent system, column dimensions, and the chromatographic activity required by the procedure.

Typical Applications

• Adsorbent and stationary packing material for column chromatography
• Separation and purification of acidic pigments
• Fractionation of strongly acidic organic substances
• Purification of suitable reaction mixtures and synthetic intermediates
• Removal of selected adsorbable impurities from laboratory samples
• Chromatographic clean-up before subsequent analysis or characterisation
• Development and optimisation of alumina-based separation methods
• Preparative organic chemistry requiring an acidic polar adsorbent

Acidic alumina is specifically documented for separating acidic pigments and strong acids, while activated aluminium oxides are established materials for column chromatography and adsorptive purification.

Common Synonyms

• Aluminium Oxide
• Aluminum Oxide
• Alumina
• Acidic Alumina
• Activated Acidic Alumina
• Active Acidic Aluminium Oxide
• Activated Aluminium Oxide, Acidic
• Activated Aluminum Oxide, Acidic
• Aluminium Sesquioxide
• Aluminum Sesquioxide

Storage Conditions

Store in a tightly closed container in a dry, clean, and well-ventilated location. Protect the product from atmospheric moisture, solvent vapours, dust, and other sources of contamination. Because alumina can adsorb moisture during storage and its chromatographic activity is influenced by water content, minimise the time the container remains open and reseal it promptly after dispensing. Preserve the material in accordance with the activity and moisture requirements stated in the approved product specification.